Req #: 234255

Department: DEPARTMENT OF IMMUNOLOGY

Posting Date: 05/15/2024

Closing Info: Open Until Filled

Salary: $3,887 - $6,334 per month

Limited Recruitment:
Other

Shift: First Shift

Notes: As a UW employee, you will enjoy generous benefits and work/life programs. For a complete description of our benefits for this position, please visit our website, click here. (https://hr.uw.edu/benefits/wp-content/uploads/sites/3/2018/02/benefits-professional-staff-librarians-academic-staff-20230701_a11y.pdf )

As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem-solving skills and dedication to build stronger minds and a healthier world.

UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty.

Parasitic worms (helminths), allergens, and certain protists all induce a “type 2” immune response that causes increased mucus production (runny nose), smooth muscle hypercontractility (coughing & sneezing), and other changes in tissue function. Why the immune system treats all of these triggers the same way remains unclear. To address this and other questions, research in the Moltke labs focuses on the initiation and regulation of type 2 immunity. Currently, the lab focuses on specialized cells in the intestinal lining called tuft cells that detect the presence of worms in the intestine using the same proteins that taste buds use to detect food. Our findings should inform the development of improved therapies for asthma, allergy, and related disorders.

The lab has an opportunity for a motivated Research Scientist/Engineer 1 (NE S UAW RSE) who will help assist lab members with experiments and help manage day-to-day operations of the lab. He/she will perform a variety of tasks to support research in the lab, including maintenance of a mouse colony and helminth stocks. The Research Scientist/Engineer is expected to use established systems/approaches to solve well-defined problems with a limited number of variables and few complex features. The Research Scientist/Engineer will also conduct experiments and tests in the immunology field that include making measurements and recording data. He/she will work under limited supervision, contribute data for use in reports and publications, and is expected to participate in regular laboratory meetings and events. The successful candidate will translate clear expectations regarding time management and task prioritization into efficient support for the research team.

DUTIES AND RESPONSIBILITIES

• 20% - Maintain a breeding colony of mice under specific-pathogen-free conditions, including animal husbandry, weaning, ear tagging, genotyping, and updating the mouse census.

• 20% - Basic molecular biology, including PCR, DNA preparation and cloning.

• 15% - Maintain laboratory stocks of worms (helminths)

• 15% - Prepare laboratory reagents.

• 5% - Multicolor flow cytometry and immunofluorescence microscopy

• 5% - Perform experimental procedures on mice, including bleeding and cell and tissue isolation.

• 5% - Organize and analyze research data.

• 5% - Participate in laboratory meetings.

• 5% - Guide the work of undergraduate employees.

• 5% - Perform related duties as required. MINIMUM REQUIREMENTS

• Bachelor's degree in Biological sciences, biochemistry, or related field and one year of relevant experience or equivalent combination of education/experience.

• Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration. ADDITIONAL REQUIREMENTS

• Experience with laboratory mice, molecular biology, immunology, and/or tissue culture. DESIRED QUALIFICATIONS

• Excellent organizational, computational and record keeping skills, attention to detail, ability to work independently but within a team environment, and willingness to work with laboratory mice. Exceptional communication and interpersonal skills. Up to one year’s experience in a related area; some or all may be in relevant educational programs. Application Process: The application process may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment, you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are access ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.

University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to, among other things, race, religion, color, national origin, sexual orientation, gender identity, sex, age, protected veteran or disabled status, or genetic information.